Pierfrancesco is a grumpy old doctor. One night he`s involved in a road collision with Mario, a rider for a food delivery service, that destroyed Mario`s bicycle. The accident also causes Pierfrancesco`s sciatica to flare up, making it impossible for him to drive. Both of their jobs are in jeopardy, but the doctor has an idea that could help them both: "remotely guided" by the doctor via a wireless headset, Mario will visit his patients, and they`ll also carry out Mario`s delivery in the doctor`s car. After a whole range of daring (mis)adventures, they will learn to support each other, and the night will end with their lives both changed for the better.